FOXBORO — The Patriots defense was down four players at Wednesday’s practice, the team’s first of the week ahead of Sunday’s home game agaisnt the Rams.

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Defensive lineman Deatrich Wise, linebacker Sione Takitaki and defensive backs Isaiah Bolden and Marcellas Dial were absent. Wise suffered a lower-body injury at the end of last Sunday’s win in Chicago, where he nabbed two sacks. Takitaki suffered a hamstring injury versus the Bears, his fourth game appearance since being activated off the Physically Unable to Perform list last month.

Bolden, a second-year corner, and Dial, a rookie, have played sparingly on defense this season. Bolden played a season-high 12 defensive snaps in Chicago. Dial is a regular on special teams.

The Patriots were also missing practice-squad offensive tackle Caleb Jones.

The Pats will release their first injury report Wednesday evening. Sunday’s kickoff is set for 1 p.m.