The NFL has flexed the Patriots-Bills Week 16 game to 4:25 p.m. ET, the NFL announced Monday.

This weekend’s game in Buffalo was originally scheduled to kick off at 1 p.m. ET. It will now be played in the later afternoon timeslot.

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This will be just the fourth Patriots game this season that won’t be played at 1 p.m. ET. The Patriots had just one primetime game, their Thursday night loss to the Jets in Week 3. They’ve played two late-afternoon games — both on the west coast — and a 9:30 a.m. ET game in London against the Jaguars.

The times and dates for the Patriots’ final two games, at home against the Chargers and Bills, are still TBD.

The Patriots have yet to play the 11-3 AFC East champion Bills. The Patriots are 14-point underdogs on the road in Week 16.