With a chance to take advantage of a banged-up New York Ranger defense, the Bruins did just enough to lose a game on Thursday at the Garden.

The Blueshirts, who were missing Jacob Trouba and Ryan Lindgren on the back end, got a pair of excuse-me Artemi Panarin goals in the second period and then immediately answered the B’s tying goal early in the third with what turned out to be the game-winner from Adam Fox to beat the Bruins, 5-2, and complete the three-game season sweep.

That was not the way the Bruins wanted to head out in a six-game road trip.

After killing off the first penalty of the game — a Brando Carlo high-stick after a Brad Marchand offensive zone turnover — the B’s got their first power play and turned up the heat for the first goal of the game.

The B’s were all over the Rangers on the PP but did not score until Fox had just stepped out of the box. The B’s peppered Igor Shesterkin, who made a pair of 10-bell saves from low in the slot on Trent Frederic. But after the second and more spectacular stop on Frederic, Shesterkin was never able to regain his equilibrium while Jake DeBrusk pounced on the loose puck in the slot and beat the Ranger netminder just inside the post at 8:04. It was DeBrusk’s 18th of the year.

That was the only goal of the period, but both teams had Grade A chances after that. First, Erik Gustafsson set up Vincent Trocheck for a redirect from the slot. Trocheck had a good chunk of the net behind Jeremy Swayman, but he tipped it wide. Hampus Lindholm was also in the right place at the right time to keep Will Cuylle from scoring into an empty net.

Then the snake-bitten Marchand (one goal in his previous 13 games) had a glittering chance from the slot but Shesterkin somehow got his pad on it.

The B’s held a 14-9 shot advantage in the first.

Neither team had much of an advantage early in a back and forth second period but the Blueshirts managed to tie it at 7:58 off a broken play. Braden Schneider tried to set up Panarin in the slot and it appeared that the B’s had broken it up. But Danton Heinen deflected the puck went right back to Panarin, whose shot from the right circle leaked through Swayman to even up the game.

From there, the Rangers controlled the play at both ends of the ice, giving up very little by way scoring chances — including on a late Bruin power play — and then took the lead with 35 seconds left in the period on a gift. Alex Wennberg forced a Lindholm turnover behind the net and it went to Panarin. The sharpshooter tried to sent it right back to Wennberg on the other side of the net but DeBrusk dove to break it up. Unfortunately, the puck went right on net and dribbled through Swayman’s pads.

The B’s nearly went down by a deuce but Panarin hit the crossbar before the horn mercifully sounded with the deficit a manageable single goal.

And the B’s evened it at 3:17. Jesper Boqvist took the puck out from behind the net and handed it off to Marchand, whose shot broke through Shesterkin. In a pileup at the net, Justin Brazeau knocked it home for his third goal in two games.

The good vibes lasted all of 40 seconds. That’s when Fox was allowed to take the puck down into the right circle and roof it over Swayman’s shoulder.

Mika Zibanejad salted it away with an empty-netter with 2:03 left and then Panarin got the vulture hat trick with another empty netter.