Making his first appearance in game action in nearly a year, Red Sox starting pitcher Lucas Giolito only made it through one inning before experiencing another injury setback.

Giolito was removed from Tuesday’s game against the Philadelphia Phillies early due to left hamstring tightness, the club announced. The right-hander had struggled with his command, throwing just 10 of his 24 pitches for strikes, and then did not return for a planned second inning.

Following his outing Giolito said he felt his hamstring tighten up on the first pitch of the game, and that he had to adjust his front leg mechanics to battle through. He said he doesn’t believe the injury is serious but isn’t sure if his next scheduled start will be impacted.

“We’ve got to look at it more. I’ve pulled my hamstring before in my career a few times and it feels very minor,” Giolito said. “Just an annoying little setback, I guess.”

Pitching in his first game since undergoing internal brace surgery in his right elbow, Giolito appeared rusty out of the gate. The 30-year-old walked Bryson Stott, allowed a double to Johan Rojas and then walked Brandon Marsh to load the bases with nobody out. He recovered by drawing back-to-back sacrifice flies and then escaped without further incident by striking out Rafael Marchan to end the threat.

The right-hander ultimately tossed just the one inning, allowing two runs on two walks and one hit. His fastball sat at 93 mph and he also worked on his changeup, cutter, slider and curveball. Following the outing Giolito said it was hard to draw any conclusions about his performance since he wasn’t throwing the way he normally does, which contributed to his erratic command.

Either way, Giolito sounded an optimistic tone that the issue will prove a minor speed bump.

“I wouldn’t even categorize this as an injury really at this point,” Giolito said. “So I’m going to do the protocol, get it looked at and it shouldn’t be too bad.”

Adam Ottavino came on in relief of Giolito in the second inning and endured his worst outing of the spring. The 39-year-old was charged with six runs on three hits, three walks and two wild pitches while recording just one out. The Phillies also stole four bases against him and catcher Connor Wong, and after coming out for minor league reliever Cooper Adams, Philadelphia delivered the haymaker when Buddy Kennedy cleared the bases with a towering two-run home run over the left field wall, putting the Phillies ahead 9-0 in the top of the second.