Have you had enough yet?

For the third time within the last week, a significant storm is set to blast the region, according to forecasters.

Just after heavy rain and strong winds pounded the Bay State Tuesday night into Wednesday, another powerful storm will impact the region Friday night into Saturday. The system is expected to again bring buckets of rain and fierce wind gusts. Any more rain will spark even more flooding.

“We’re looking at 1 to 2 inches of rain, which is less than this past storm fortunately, but it will exacerbate the flooding issues,” Bryce Williams, meteorologist at the National Weather Service’s Boston office, told the Herald on Wednesday.

After a nor’easter dumped more than a foot of snow on many parts of the region, the rain storm Tuesday night sparked flooding in many spots. Nearly 5 inches of rain was measured in Hopkinton.

The National Weather Service issued a “Flood Warning” for many rivers in Massachusetts, including the Charles River, Neponset River, Sudbury River, Shawsheen River, Blackstone River, and Taunton River.

A widespread 2 to 4 inches of rain fell Tuesday night into Wednesday, along with rapid snowmelt. That resulted in many rivers and streams flooding.

Up in New Hampshire, videos went viral of significant flooding at Hampton Beach.

“An emergency has been declared as a result of extremely high seas and flooding,” the Hampton Police Department posted. “Ocean Boulevard is temporarily closed down. Please avoid the area. If you live in the area please shelter in place.”

This is unbelievable. Major flooding at Hampton Beach, NH this morning from the storm! @weatherchannel @ABC @WCVB @AssignGuy @NBC10Boston @NWSBoston @NWSGray @JimCantore @jlcouture @7News @accuweather @AccuRayno @NBCNews @GMA @Ginger_Zee pic.twitter.com/hWz6wjV9CM

— Henry Swenson (@HenrySwenson) January 10, 2024

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Due to the heavy rain, the Boston Public Health Commission sent out a public health warning about sewage discharges — also known as a combined sewer overflows — in the Charles River and Boston Harbor.

The sewage discharges were reported at the following spots: Charles River upstream of the Boston University Bridge, Charles River at Stoney Brook, Charles River at the Miriam and Sidney Stoneman Playground, Jeffries Point in East Boston, and the Fort Point Channel.

“The public is advised to avoid contact with affected water bodies for at least 48 hours after a sewage discharge or overflow, during rainstorms, and for 48 hours after rainstorms end, due to increased health risks from bacteria or other pollutants associated with urban stormwater runoff and discharges of untreated or partially treated wastewater,” the public health warning states.

“A combined sewer overflow occurs when a large storm overwhelms the combined sewerage system causing rainwater to mix with wastewater and discharge to a nearby water body,” the warning adds. “This prevents sewage backups into homes and businesses.”

The highest wind gusts during the storm were reported along Cape Cod: 69 mph recorded on Scusset Beach in Sagamore, 65 mph in Chatham and Dennis, and 64 mph in Wellfleet.

There were several reports of wind damage along the coast. Trees were toppled and power lines were down.

More gusty winds and heavy rainfall are now in store for this weekend, with any additional rainfall only exacerbating flooding.

“The strongest wind gusts are looking like Friday night and early Saturday,” said Williams, of the National Weather Service.

While there won’t be the snowmelt element like in this past storm, the ground is already saturated and rivers and streams are swollen in many locations.

Coastal flooding will also be a concern with this system.