The Patriots will fly to Germany without two offensive starters after ruling out left tackle Trent Brown and wide receiver DeVante Parker following Tuesday’s practice.

Brown, who was spotted in the Patriots’ locker room Thursday morning but declined to speak to reporters, was inactive for last week’s loss to the Commanders. Veteran Conor McDermott filled in at left tackle and is likely to be elevated off the practice squad again for Sunday’s game.

Parker also missed last weekend’s loss, when third-year receiver Jalen Reagor took on a bigger role in his place at the “X” receiver position. The Pats also have JuJu Smith-Schuster, Demario Douglas, Tyquan Thornton and Kayshon Boutte at the position.

The Patriots will fly to Frankfurt, Germany, overnight Thursday and release their final injury report Friday. Sunday’s kickoff against the Colts is set for 9:30 a.m. ET

Both teams’ complete injury reports are below.

PATRIOTS

Out

OT Trent Brown, Not Injury Related (Personal) / Ankle

WR DeVante Parker, Concussion

CB J.C.Jackson, Not Injury Related (Personal)

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Limited participation

DL Christian Barmore, Knee

LB Ja’Whaun Bentley, Hamstring

CB Myles Bryant, Chest

WR Demario Douglas, Ankle

CB Jonathan Jones, Knee

OL Vederian Lowe, Ankle

DL Deatrich Wise, Shoulder

COLTS

Did not participate

CB JuJu Brents, Quadricep

WR Josh Downs, Knee

TE Drew Ogletree, Foot

Limited participation

WR Alec Pierece, Ankle

LB Zaire Franklin, Knee

Full participation

CB Tony Brown, Concussion

T Braden Smith, Hip/Wrist