The Celtics lost to an injury-depleted opponent on their home floor Wednesday night. They didn’t let that happen again on Friday.

Boston rode one of its best shooting performances of the season to a 125-117 win over the Toronto Raptors at TD Garden.

Payton Pritchard led all scorers with 27 points on 12-of-19 shooting, adding eight assists and five rebounds. Jaylen Brown was less efficient from the field (6-for-16) but went 12-for-13 from the foul line to finish with 25-7-8. Sam Hauser scored 19, went 5-for-7 from 3-point range and was a team-best plus-23 in his 32 minutes.

Team-wide, the Celtics shot 54%, 50% from three and 89.5% on free throws, hitting those marks in the same game for the first time since January 2024 and just the third time in Joe Mazzulla’s head-coaching tenure.

The Raptors were playing without three injured starters: leading scorer Brandon Ingram, All-Star wing Scottie Barnes and center Jakob Poeltl. They attempted to outgun the Celtics by shooting 47 3-pointers — 19 more than three-happy Boston — and making 18 of them. Despite its absences, Toronto played 11 different players and got 40 points from its bench, but Boston took control in the fourth quarter and withstood a late comeback bid.

The win allowed the 24-13 Celtics to remain ahead of the 23-16 Raptors in the Eastern Conference standings. The teams came in ranked third and fourth in the East, respectively, behind Detroit and New York.

Hauser, starting his fourth straight game since leapfrogging Jordan Walsh on the depth chart, hit his first four 3-pointers to spearhead a red-hot Celtics start. Boston started 10-for-13 from the field, with Brown and Pritchard also finding success attacking the basket during that opening stretch.

Hugo Gonzalez contributed a second-chance layup and a chasedown block (which was awarded after a successful Celtics challenge), and the Celtics led 37-30 after one quarter.

They struggled to gain separation, however, against a shorthanded Raptors team that shot 11-for-25 from behind the arc in the first half. A three by RJ Barrett, moments after Colin Murray-Boyles posterized Pritchard with a powerful lob dunk, capped a 10-1 run that gave Toronto its first lead of the night, 47-37.

The Celtics responded with a flurry of their own, led by Anfernee Simons.

Simons saw his lightest first-quarter workload of the season — he sat nearly the entire period, only checking in with 4.5 seconds remaining — but scored 11 points in the second on 4-of-5 shooting. The sixth man put Boston back in front with a 3-pointer, then proceeded to score or assist on the Celtics’ next four made baskets. Simons hit two more threes on consecutive trips late in the first half, helping Boston take a 68-60 lead into the locker room.

The Raptors lost their shooting touch in the third quarter (3-for-12 from deep), and the Celtics looked poised to pull away. Pritchard scored 12 in the quarter, including a midrange jumper that stretched Boston’s lead to 93-73.

Brown did not make a field goal in the quarter, but he was 6-for-6 from the foul line, receiving “MVP” chants from the Garden crowd before each attempt. Two nights earlier, Brown had complained about what he viewed as an unfair whistle in Boston’s loss to the Denver Nuggets, during which he drew just two shooting fouls.

But Toronto turned a series of turnovers and Celtics misses into fast-break buckets at the other end. A full-speed tomahawk dunk by two-way guard Alijah Martin over White cut the deficit to 11. Two minutes into the fourth quarter, it was down to six, 99-93.

Hauser, who’s taken nearly 90% of his field goals from 3-point range this season, scored an at-the-rim putback and a 15-footer on back-to-back possessions to put the Celtics up 110-103. Brown followed with a driving dunk over Sandro Mamukelashvili, then, after a Hauser steal, converted an and-one layup in transition.

A 3-pointer from White, who paused to avoid a Murray-Boyles closeout before letting it fly, made it 120-106 with 3:21 to play.

Boston will have a quick turnaround before hosting the Spurs on Saturday (8 p.m.). San Antonio owns the NBA’s third-best record and one of its most uniquely talented players in 7-foot-4 superstar Victor Wembanyama.

Saturday’s game also will be the first one back in Boston for former Celtics big man Luke Kornet. The 2024 NBA champion attended Friday’s game as a fan, watching from beneath the basket and gladhanding with Celtics minority owner Wyc Grousbeck, majority owner Bill Chisholm and former teammate Jayson Tatum.