Local musician Mark Erdody is not the kind of guy who likes to accept much help from his friends. But this weekend, he’ll have to get used to it.

Erdody is known as singer, guitarist and bassist of the bands Kudgel and Black Helicopter, and as one of the nicer blokes on the local scene. Over the past year he’s been getting treatment for Hodgkin’s lymphoma— but as a holistic healer and substance abuse counsellor, he didn’t have much paid healthcare. So to help out with medical bills, he’s recruited a dream lineup of local artists — especially if you remember back to the late ‘90s and your tastes run to the louder, more adventurous side of things.

“I basically called up all my heroes,” he said this week. “Next thing I knew, I had an afternoon and an evening filled up. The kindness of people was pretty amazing.” As for his musical taste, “Basically, I am hopelessly indie rock. My own band was pretty noisy and screamy, but I always thought we had hooks as well. And I love that era, people like Conley and Brokaw (Clint Conley and Chris Brokaw, from Mission of Burma and Come) always meant a lot to me. I was living behind Man Ray (on Central Square) at that time and everything was happening at TT the Bear’s Place and the Middle East. I even met my wife at Green Street.”

He wound up pulling together two all-star lineups for shows at The Middle East. The afternoon show will be headlined by Minibeast — the wildly creative band fronted by ex-Burma member Peter Prescott — and will include the Boston Typewriter Orchestra, a special one for Erdody since his dad was a typewriter repairman. And the evening show will feature a big round of notable names including Seana Carmody (ex-Swirlies), Jim Buni (ex-Buttercup), and Hilken Mancini (ex-Fuzzy), all playing in different combinations.

The night show will also feature two guys who started two of the most important record labels of that era. Mark Robinson, who produced some great indie-pop on his TeenBeat label, will play songs from his long-defunct band Unrest. Even rarer will be an onstage appearance by Gerard Cosloy, whose Matador label launched the careers of Liz Phair, Pavement, Guided by Voices and countless others. He’ll be flying in from Austin just to do this show. “Freaking Cosloy, can you believe it?” Erdody says. “If you think about my favorite records from that era, he had his hands in most of them.”

Also notable will be a one-time reunion of Consonant, the band that Brokaw and Conley had together (with bassist Winston Braman) around 2001, just before Conley rejoined Mission of Burma. The supergroup will get more super this time, with Prescott (who switched to guitar in Minibeast) playing drums for one of the first times since Burma’s breakup. “I loved the band and was sad to see if go,” Brokaw said in a separate interview. “When Mark asked me to get involved I said sure, but didn’t know what I’d be doing. Then Clint and I started talking and we thought we could actually do this.”

Though he recently finished an aggressive round of chemotherapy, Erdody also plans to be onstage Saturday, doing a Black Helicopter set that will revisit Kudgel material. “I wasn’t sure if we’d be able to do the Kudgel songs because that’s so physical, but that’s the power of rock. It’s something you always have inside, no matter what phase of life you’re in. Sometimes it’s just a spark, but this weekend it will be a roaring fire.”